Microarrays

4-PLEX Microarray

Close-up of little boy suffering from asthma taking inhalationQuantitative detection of serum antibodies helps physicians to determine whether their pediatric asthma patients suffer from virus- or allergen-triggered asthma. For this purpose, Viravaxx has invented and commercializes innovative 4-PLEX microarray technology using chips spotted with recombinant viral proteins, synthetic rhinovirus peptides (A, B and C species), and RSV-derived peptides. 

 

4-PLEX Microarray

Viravaxx’ 4-PLEX Microarray is for Research Use Only. It requires only small blood samples. No extensive sample preparation. Viravaxx offers custom spotting of antigens – for orders please contact us at info@viravaxx.com or visit our webshop.

SLIDE-DECK-RESPIRATORY-CHIP

 

Background publications:

  • Niespodziana K, Borochova K, Pazderova P, Schlederer T, Astafyeva N, Baranovskaya T, Barbouche MR, Beltyukov E, Berger A, Borzova E, Bousquet J, Bumbacea RS, Bychkovskaya S, Caraballo L, Chung KF, Custovic A, Docena G, Eiwegger T, Evsegneeva I, Emelyanov A, Errhalt P, Fassakhov R, Fayzullina R, Fedenko E, Fomina D, Gao Z, Giavina-Bianchi P, Gotua M, Greber-Platzer S, Hedlin G, Ilina N, Ispayeva Z, Idzko M, Johnston SL, Kalayci Ö, Karaulov A, Karsonova A, Khaitov M, Kovzel E, Kowalski ML, Kudlay D, Levin M, Makarova S, Matricardi PM, Nadeau KC, Namazova-Baranova L, Naumova O, Nazarenko O, O’Byrne PM, Osier F, Pampura AN, Panaitescu C, Papadopoulos NG, Park HS, Pawankar R, Pohl W, Renz H, Riabova K, Sampath V, Sekerel BE, Sibanda E, Siroux V, Sizyakina LP, Sun JL, Szepfalusi Z, Umanets T, Van Bever HPS, van Hage M, Vasileva M, von Mutius E, Wang JY, Wong GWK, Zaikov S, Zidarn M, Valenta R. Toward personalization of asthma treatment according to trigger factorsJ Allergy Clin Immun. (2020). 145 (6): 1529-1534; https://doi.org/10.1016/j.jaci.2020.02.001.

  • Niespodziana K, Stenberg-Hammar K, Megremis S, Cabauatan CR, Napora-Wijata K, Vacal PC, Gallerano D, Lupinek C, Ebner D, Schlederer T, Harwanegg C, Söderhäll C, van Hage M, Hedlin G, Papadopoulos NG, Valenta R. PreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze. Nature Commun. (2018); 9(1):2382; https://doi.org/10.1038/s41467-018-04591-0.

  • Megremis S, Niespodziana K, Cabauatan C, Xepapadaki P, Kowalski ML, Jartti T, Bachert C, Finotto S, West P, Stamataki S, Lewandowska-Polak A, Lukkarinen H, Zhang N, Zimmermann T, Stolz F, Neubauer A, Akdis M, Andreakos E, Valenta R, Papadopoulos NG. Rhinovirus Species-Specific Antibodies Differentially Reflect Clinical Outcomes in Health and Asthma. Am J Respir Crit Care Med. (2018); 198(12):1490-1499; https://doi.org/10.1164/rccm.201803-0575OC.